Gene Knockin • CRISPR Knockin
Can't find a ready-to-go stable knockin cell line for your assay? Reach out to our team for custom CRISPR knockin cell line service.
CRISPR knockin cell line service
Bacteria use CRISPR to detect and defend against viruses by storing their DNA fragments and activating the Cas9 nuclease to degrade invading DNA. By harnessing this mechanism, researchers can introduce guide sequences (sgRNA) to create precise gene knockin. These CRISPR knockin cell lines are crucial for studying gene function, understanding disease mechanisms, and developing new treatments.
At Acres Biosciences, we specialize in CRISPR knockin cell line generation. Leveraging advanced technologies and our seasoned expertise, we streamline your research process and amplify its impact, accelerating your discoveries and innovations.
Point Mutation Knockin Cell Line
Cell Types: Various types of cells including commonly used cell lines, tumor cell lines, and primary cell lines
Deliverables: Two point mutation cell clones
Validation Method: Sequencing
Timeline: 12-25 weeks (cell clone)
Reporter Knockin Cell Line
Customization Options: Cell pool or single clone; various types of reporters
Cell Types: Various types of cells including commonly used cell lines, tumor cell lines, and primary cell lines
Deliverables: One CRISPR knockin cell pool or two knockin single clones
Validation Method: Sequencing and reporter assay upon requestor
Timeline: 8-11 weeks (cell pool), 16-24 weeks (cell clone)
Custom Gene Knockin Cell Line
Customization Options: Cell pool or single clone; flexible size of knock-in fragments
Cell Types: Various types of cells including commonly used cell lines, tumor cell lines, and primary cell lines
Deliverables: One CRISPR knockin cell pool or two knockin single clones
Validation Method: Sequencing and customized assays upon request
Timeline: 8-11 weeks (cell pool), 16-24 weeks (cell clone)
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